DART - Dupuytren's Advocates for Radiation Therapy

                 A Worldwide Facebook forum led by members to discuss privately how to cope  with the disease and treatment options available

What is Ledderhose Disease? 

Also known as Plantar Fibromatosis/Plantar Fibroma

  • Ledderhose, and plantar fibromatosis, is a benign disease/condition that causes a non-malignant thickening of the feet's deep connective tissue also known as the fascia.
  • The condition can produce nodules or cords that start growing along tendons of the foot.
  • The nodules are typically slow growing and most often found in the middle area of the plantar fascia. This tissue is somewhat aggressive and progressively and replaces the normal plantar tissue during the active stage.
  • Ledderhose is more common in men than woman and it is sometimes associated with other forms of fibromatosis, known as Dupuytren’s disease in the hand, Peyronie’s disease in the penis, or knuckle pads on the fingers. Appx. 25 percent of patients have Ledderhose and one of the other related diseases.
  • Contracture of the toes is rare, but not unheard of.   It is much less than the contraction percentages from Dupuytren's contracture, which is in the hands.
  • Ledderhose is most frequently present  near the highest point of the arch where the thinner skin appears on the sole. The lump is can be painless, but some pain can be experienced is when the nodule rubs on the shoe or floor or is in an active growth mode.  The overlying skin is freely movable, and contracture of the toes does not occur in the initial stages.  It is known to affect the nerves to the big toe. 
  • The disease is more commonly associated with a family history of the disease and may be higher occurance in men and those people with Dupuytren's Disease (Palmar fibromatosis) up to 65% of the time.
  • Symptoms can be itching, burning, pain on the base of the foot and/or toes.

An actual FORUM MEMBER's experience!

Who treats Plantar Fibromatosis/Ledderhose Disease?

Ledderhose (plantar fibromatosis)

  • Podiatrists treat Ledderhose disease mainly by modifying footwear, providing custom orthotics and in some cases cortisone injections. Cryosurgery is offered by a few podiatrists. It is a minimally invasive procedure that does not remove the nodule, rather it aims to kill the nerves around the nodule to eliminate pain.

  • A foot surgeon may diagnosis the disease, however, only in extreme cases, surgery has been performed to remove the fibroma but surgery is generally not recommended for Ledderhose.  It is known that surgery disturbs the tissue and can cause the disease to become active and produce additional growth.

  • A plastic surgeon in California  is known to use Xiaflex "off label" to inject into the nodules based on his website.

  • Radiation oncologists are specialists who treat both Dupuytren's and Ledderhose with low dose radiation therapy to attempt to stop the progression of the disease.


ZERO      Happy, not hurting at all
TWO       Hurts a little
FOUR     Hurts more than a little
SIX         Hurts even more
EIGHT    Hurts a lot
TEN        Hurts as much as I can imagine

Prior to radiation therapy this forum member charted their pain a 10 out of 10 for over two years.

Within days of the first session of radiation therapy the pain was down to  a strong 8/9. 

Within 3 months of the first session of radiation therapy, the pain was down to a 2/3.

Within 3 months of my second session of radiation therapy, the pain is a constant 0/1. 

Within 12 months post radiation therapy there is no pain at all to report.  The nodules are flat, while the tissue remains, there is no pain.  There has also been no recurrance of this disease several years later.


Dupuytren's Advocates for Radiation Therapy

One of our forum members Plantar Fibromaosis (Ledderhose) in April 2015.  The larger nodule is growing on the tendon.  There is a small undetectable nodule just above  this. This nodule started growing in 2011 and in 2012 member was officially diagnosed when it finally came to surface.

Why is low dose radiation used?
Low dose radiation therapy is used to stop the progression of the disease